Mix the flour, salt, and pepper on a plate and dredge the tilapia fillets in the mixture.
Pour the oil into a large skillet and heat it over medium heat. Cook each piece of tilapia for about 3 minutes on each side (until cooked through). Set aside.
Combine the orange juice, lemon/lime juice, soy sauce, and honey in a medium bowl. Pour the sauce into the pan and heat through. Add the fish to the pan and cook for a minute, flipping once and making sure to cover the fish with the sauce.
Transfer the fish to a platter and pour the remaining sauce on the fish. Serve immediately.